Old English Inns is thought to be in greatest danger because of a decline in visitors to rural areas.
The disease would add further difficulties to a company that has already suffered from flooding.
• Brake Bros has warned it could suffer if more public events are cancelled because of foot-and-mouth outbreaks.
The supplier of frozen and chilled food to caters and restaurants said its fear was for its customers which had been hit by a decline in visitors to rural areas.
But it said its wide range of meat products should help the company cope with further incidences of the virus.
Brake announced annual pre-tax profits after goodwill, up from £36.1m to £36.6m on sales up 16.8% to £1.1bn.
It wants to reduce its dependence on its UK market by buying more food companies in France.
Floods, rail and petrol problems affected the results.